Pub. Date : 1987 Dec
PMID : 3678136
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The model of the serum PRL surge generated in the ovariectomized rat after estradiol benzoate (EB) treatment was used to study the relationship between serum and pituitary PRL levels and pituitary PRL mRNA levels. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
2 | The model of the serum PRL surge generated in the ovariectomized rat after estradiol benzoate (EB) treatment was used to study the relationship between serum and pituitary PRL levels and pituitary PRL mRNA levels. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
3 | At other times, serum PRL levels in the EB group were the same as control values. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
4 | EB treatment also elicited a marked increase in pituitary PRL content at all time periods examined except during (1600 and 2000 h) and after the PRL surge (2400 h on day 3) when there was a significant reduction in stored pituitary PRL. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
5 | EB treatment also elicited a marked increase in pituitary PRL content at all time periods examined except during (1600 and 2000 h) and after the PRL surge (2400 h on day 3) when there was a significant reduction in stored pituitary PRL. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
6 | EB treatment also elicited a marked increase in pituitary PRL content at all time periods examined except during (1600 and 2000 h) and after the PRL surge (2400 h on day 3) when there was a significant reduction in stored pituitary PRL. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
7 | The pituitary PRL mRNA content in the EB-treated group was significantly elevated (4- to 6-fold) over control levels throughout the study. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
8 | Furthermore, PRL mRNA levels in EB-treated rats were significantly higher at 2000 and 2400 h on day 3 than at other time periods. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
9 | Furthermore, the facts that serum PRL levels were elevated only at certain times (1200-2000 h on day 3) while PRL mRNA content was increased at all times in the EB-treated rats suggest a differential regulation between PRL release and biosynthesis. | estradiol 3-benzoate | prolactin | Rattus norvegicus |
10 | Furthermore, the facts that serum PRL levels were elevated only at certain times (1200-2000 h on day 3) while PRL mRNA content was increased at all times in the EB-treated rats suggest a differential regulation between PRL release and biosynthesis. | estradiol 3-benzoate | prolactin | Rattus norvegicus |