Title : Processing of psoralen adducts in an active human gene: repair and replication of DNA containing monoadducts and interstrand cross-links.

Pub. Date : 1987 Aug 28

PMID : 3621344






4 Functional Relationships(s)
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1 We have examined DNA repair in the dihydrofolate reductase (DHFR) gene in cultured human cells treated with 4"-hydroxymethyl-4,5",8-trimethylpsoralen (HMT) using a newly developed assay for interstrand DNA cross-linking in defined genomic sequences. hydroxymethyltrioxsalen dihydrofolate reductase Homo sapiens
2 We have examined DNA repair in the dihydrofolate reductase (DHFR) gene in cultured human cells treated with 4"-hydroxymethyl-4,5",8-trimethylpsoralen (HMT) using a newly developed assay for interstrand DNA cross-linking in defined genomic sequences. hydroxymethyltrioxsalen dihydrofolate reductase Homo sapiens
3 We have examined DNA repair in the dihydrofolate reductase (DHFR) gene in cultured human cells treated with 4"-hydroxymethyl-4,5",8-trimethylpsoralen (HMT) using a newly developed assay for interstrand DNA cross-linking in defined genomic sequences. hydroxymethyltrioxsalen dihydrofolate reductase Homo sapiens
4 We have examined DNA repair in the dihydrofolate reductase (DHFR) gene in cultured human cells treated with 4"-hydroxymethyl-4,5",8-trimethylpsoralen (HMT) using a newly developed assay for interstrand DNA cross-linking in defined genomic sequences. hydroxymethyltrioxsalen dihydrofolate reductase Homo sapiens