Title : Novobiocin interferes with the binding of transcription factors TFIIIA and TFIIIC to the promoters of class III genes.

Pub. Date : 1987 Jun 11

PMID : 3588299






2 Functional Relationships(s)
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1 Novobiocin interferes with the binding of transcription factors TFIIIA and TFIIIC to the promoters of class III genes. Novobiocin general transcription factor IIIC subunit 1 Homo sapiens
2 Using DNase I footprinting, we show here that novobiocin inhibits the specific binding of polymerase III transcription factors TFIIIA and TFIIIC to the promoters of the 5S RNA and VA RNA genes, respectively. Novobiocin general transcription factor IIIC subunit 1 Homo sapiens