Title : 3,4,5-O-tricaffeoylquinic acid with anti-radiation activity suppresses LPS-induced NLRP3 inflammasome activation via autophagy in THP-1 macrophages.

Pub. Date : 2022 Jul

PMID : 35633614






1 Functional Relationships(s)
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1 Furthermore, we found that the autophagy inhibitor chloroquine, not the proteasome inhibitor MG132, could counteract the promoting effect of tCQA on NLRP3 degradation and the inhibitory effect on cell death. Chloroquine NLR family pyrin domain containing 3 Homo sapiens