Pub. Date : 2022 May 20
PMID : 35627777
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Modification Effect of PARP4 and ERCC1 Gene Polymorphisms on the Relationship between Particulate Matter Exposure and Fasting Glucose Level. | Glucose | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
| 2 | In particular, elders with PARP4 G-C-G or ERCC1 T-C haplotype were susceptible to PMs exposure in relation to glucose levels (PARP4 G-C-G: beta = 2.6 and p = 0.0006 for PM10, beta = 3.5 and p = 0.0009 for PM2.5-10, and beta = 1.6 and p = 0.0020 for PM2.5; ERCC1 T-C: beta = 2.2 and p = 0.0016 for PM10, beta = 3.5 and p = 0.0003 for PM2.5-10, and beta = 1.2 and p = 0.0158 for PM2.5). | Glucose | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
| 3 | Our results indicated that genetic polymorphisms of PARP4 and ERCC1 could modify the relationship between PMs exposure and fasting glucose level in the elderly. | Glucose | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |