Pub. Date : 2022 May 27
PMID : 35618957
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | On one side iron is essential to terminal erythropoiesis for hemoglobin production, on the other erythropoiesis may increase iron absorption through the production of erythroferrone, the erythroid hormone that suppresses hepcidin expression Also erythropoietin production is modulated by iron through the iron regulatory proteins-iron responsive elements that control the hypoxia inducible factor 2-alpha. | Iron | erythropoietin | Homo sapiens |
| 2 | The second transferrin receptor, an iron sensor both in the liver and in erythroid cells modulates erythropoietin sensitivity and is a further link between hepcidin and erythropoiesis. | Iron | erythropoietin | Homo sapiens |