Title : Ultrapotent and broad neutralization of SARS-CoV-2 variants by modular, tetravalent, bi-paratopic antibodies.

Pub. Date : 2022 May 31

PMID : 35617963






1 Functional Relationships(s)
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Protein Name
Organism
1 The tetravalent nAb binds to the spike protein trimer at least 100-fold more tightly than bivalent IgGs (apparent KD < 1 pM) and neutralizes a broad array of SARS-CoV-2 pseudoviruses, chimeric viruses, and authentic viral variants with high potency. nab surface glycoprotein Severe acute respiratory syndrome coronavirus 2