Title : Crosstalk between IL-15Rα+ tumor-associated macrophages and breast cancer cells reduces CD8+ T cell recruitment.

Pub. Date : 2022 Jun

PMID : 35615815






1 Functional Relationships(s)
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1 Further investigation showed that IL-15Ralpha+ TAMs reduced the protein levels of chemokine CX3C chemokine ligand 1 (CX3CL1) in tumor cells to inhibit the recruitment of CD8+ T cells by releasing the IL-15/IL-15Ralpha complex (IL-15Rc). tams CD8a molecule Homo sapiens