Title : NLRP3/Caspase-1-Mediated Pyroptosis of Astrocytes Induced by Antipsychotics Is Inhibited by a Histamine H1 Receptor-Selective Agonist.

Pub. Date : 2022

PMID : 35615587






1 Functional Relationships(s)
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1 Twenty-four hour treatment with olanzapine, quetiapine, risperidone, or haloperidol dose-dependently increased the protein expression of astrocytic NLRP3, NLRP6, caspase-1, caspase-4, and GSDMD. Haloperidol NLR family pyrin domain containing 3 Homo sapiens