Title : A Novel Immune-Prognosis Index Predicts the Benefit of Lung Adenocarcinoma Patients.

Pub. Date : 2022

PMID : 35614936






3 Functional Relationships(s)
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1 The comprehensive results showed that patients in the IPI-high subgroup were exhibited characters as metabolism-related signaling pathways activation, lower TP53 and TTN mutation rate, more infiltrations of CD8 T cells, dendritic cells and macrophages M1, especially earned more benefit from ICB treatment. diprotin A tumor protein p53 Homo sapiens
2 In contrast, patients in the IPI-low subgroup were exhibited characters as p53 signaling pathways activation, higher TP53 and TTN mutation rate, more infiltrations of resting memory CD4 T cells, macrophages M2, immune-suppressive response and less benefit from ICB treatment. diprotin A tumor protein p53 Homo sapiens
3 In contrast, patients in the IPI-low subgroup were exhibited characters as p53 signaling pathways activation, higher TP53 and TTN mutation rate, more infiltrations of resting memory CD4 T cells, macrophages M2, immune-suppressive response and less benefit from ICB treatment. diprotin A tumor protein p53 Homo sapiens