Title : Acupuncture improves the structure of spastic muscle and decreases spasticity by enhancing GABA, KCC2, and GABAAγ2 in the brainstem in rats after ischemic stroke.

Pub. Date : 2022 Jun 8

PMID : 35594431






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1 RESULTS: In SAS models, hindlimb motor ability was decreased, neurologic deficits and spasticity were induced, the proportion of type I muscle fibers in spastic muscle was increased, and the expressions of gamma-aminobutyric acid (GABA), KCC2, and the GABAAgamma2 subunit of the pentameric GABAA receptor in the brainstem were decreased. gamma-Aminobutyric Acid solute carrier family 12 member 5 Rattus norvegicus