Title : Reverse anti-breast cancer drug resistance effects by a novel two-step assembled nano-celastrol medicine.

Pub. Date : 2022 Jun 1

PMID : 35583119






1 Functional Relationships(s)
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1 Celastrol (CST) was directly assembled into a discrete nanomedicine by precipitation, and then CST nanoparticles (CNPs) inhibited drug efflux pumps by activating HSF-1 expression and promoting HSF-1 translocation into nucleus to suppress the Pgp expression. celastrol phosphoglycolate phosphatase Homo sapiens