Title : Improved engraftment and therapeutic efficacy by human genome-edited hematopoietic stem cells with Busulfan-based myeloablation.

Pub. Date : 2022 Jun 9

PMID : 35573043






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Compared with sub-lethal irradiation, Busulfan conditioning enhanced the engraftment of edited CD34+ cells in the bone marrow, as well the long-term homing and survival of bone-marrow-derived cells in viscera, and in the CNS, resulting in higher transgene expression and biochemical correction in these organs. Busulfan CD34 molecule Homo sapiens