Pub. Date : 2022 May 5
PMID : 35558858
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Spontaneous attraction of GOQDs loaded with Carmofur toward the binding pocket of the main protease (Mpro) resulted in the penetration of Carmofur into the active catalytic region. | carmofur | NEWENTRY | Severe acute respiratory syndrome-related coronavirus |
2 | Spontaneous attraction of GOQDs loaded with Carmofur toward the binding pocket of the main protease (Mpro) resulted in the penetration of Carmofur into the active catalytic region. | carmofur | NEWENTRY | Severe acute respiratory syndrome-related coronavirus |
3 | It was found that the presence of GOQD as an effective carrier in the loading and delivery of Carmofur inhibitor affected the structural conformation of Mpro. | carmofur | NEWENTRY | Severe acute respiratory syndrome-related coronavirus |
4 | These results suggested that the binding pocket of Mpro is not stable during the interaction with the Carmofur-GOQD complex. | carmofur | NEWENTRY | Severe acute respiratory syndrome-related coronavirus |