Title : CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer.

Pub. Date : 2022 May 12

PMID : 35550508






1 Functional Relationships(s)
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1 Integrative transcriptomic, metabolomic and functional data reveal that hyperactivation of the serine-glycine-one-carbon network is a metabolic hallmark inherent to CDK12-induced tumorigenesis. Serine cyclin-dependent kinase 12 Mus musculus