Title : Adsorption of Pulmonary and Exogeneous Surfactants on SARS-CoV-2 Spike Protein.

Pub. Date : 2022 May 4

PMID : 35547841






1 Functional Relationships(s)
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1 With examples of zwitterionic dipalmitoyl phosphatidyl choline, cholesterol, and anionic sodium dodecyl sulphate, we show that surfactants form micellar aggregates that selectively adhere to the specific regions of S1 domain of the Spike protein that are responsible for binding with ACE2 receptors and virus transmission into the cells. Cholesterol surface glycoprotein Severe acute respiratory syndrome coronavirus 2