Pub. Date : 2022 Jul 15
PMID : 35545133
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MAIN METHODS: By radioactive labeling and metabolite quantification, we studied the function of FABP5 in fatty acid metabolism using genetic/pharmacologic inhibition and overexpression models in LUAD cell lines. | Fatty Acids | fatty acid binding protein 5 | Homo sapiens |
| 2 | FABP5 regulates lipid metabolism, diverting fatty acids towards complex lipid synthesis, whereas it does not affect their catabolism in vitro. | Fatty Acids | fatty acid binding protein 5 | Homo sapiens |
| 3 | Moreover, FABP5 is required for de novo fatty acid synthesis and regulates the expression of enzymes involved in the pathway (including FASN and SCD1). | Fatty Acids | fatty acid binding protein 5 | Homo sapiens |