Pub. Date : 2022 Jul 1
PMID : 35525317
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cisplatin-induced pyroptosis is mediated via the CAPN1/CAPN2-BAK/BAX-caspase-9-caspase-3-GSDME axis in esophageal cancer. | Cisplatin | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 2 | Mechanistically, we uncovered a novel mechanism whereby cisplatin induced pyroptosis via activation of a CAPN1/CAPN2-BAK/BAX-caspase-9-caspase-3-GSDME signaling axis in esophageal cancer cells. | Cisplatin | BCL2 associated X, apoptosis regulator | Homo sapiens |