Title : Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein.

Pub. Date : 2022 Aug 5

PMID : 35525080






1 Functional Relationships(s)
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Protein Name
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1 After structural optimization for several rounds, C11 displayed a relatively better affinity with 14-3-3eta, as well as the best inhibitory activities against several typical human liver cancer cell lines, including Bel-7402, SMMC-7721, SNU-387, Hep G2 and Hep 3B cells. 4-(1H-Pyrrol-1-yl)aniline RNA polymerase III subunit K Homo sapiens