Title : Early pregnancy vitamin D status is associated with blood pressure in children: An Odense Child Cohort study.

Pub. Date : 2022 May 3

PMID : 35511609






4 Functional Relationships(s)
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1 In adjusted analyses, a 10 nmol/L increase of s-25(OH)D in early pregnancy associated with a 0.3/0.2 mmHg lower SBP/DBP at 5 years (p <0.05). 25(oh)d D-box binding PAR bZIP transcription factor Homo sapiens
2 Optimal s-25(OH)D (>75 nmol/L) in early pregnancy was associated with lower 5-year SBP and DBP, beta (95%CI) -1.45 (-2.6,-0.3), and -0.97 (-1.9,-0.1), compared with reference s-25(OH)D 50-74.9 nmol/L. 25(oh)d D-box binding PAR bZIP transcription factor Homo sapiens
3 Two-stage analysis combining early pregnancy, late pregnancy, and cord s-25(OH)D data showed an inverse association with 5-year SBP and DBP for boys (p <0.025) with significant sex-difference for DBP (pinteraction=0.004). 25(oh)d D-box binding PAR bZIP transcription factor Homo sapiens
4 Two-stage analysis combining early pregnancy, late pregnancy, and cord s-25(OH)D data showed an inverse association with 5-year SBP and DBP for boys (p <0.025) with significant sex-difference for DBP (pinteraction=0.004). 25(oh)d D-box binding PAR bZIP transcription factor Homo sapiens