Title : Determining the Effects of Chronic Kidney Disease on Organic Anion Transporter1/3 Activity Through Physiologically Based Pharmacokinetic Modeling.

Pub. Date : 2022 May 5

PMID : 35508593






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1 METHODS: Physiologically based pharmacokinetic models were constructed for four OAT1/3 substrates in healthy individuals: acyclovir, meropenem, furosemide, and ciprofloxacin. Acyclovir solute carrier family 22 member 6 Homo sapiens