Title : Non-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7.

Pub. Date : 2022 May 3

PMID : 35504877






1 Functional Relationships(s)
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1 While ATP binding cassette subfamily C member 5 (ABCC5) has been reported to regulate multiple drug resistance, its drug-efflux function may not be the main reason underlying resistance to enzalutamide, an androgen receptor inhibitor. enzalutamide androgen receptor Homo sapiens