Pub. Date : 2022 May 18
PMID : 35503561
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Specifically, SARS-CoV-2 spike protein-induced MC degranulation resulted in alveolar-capillary injury, while pretreatment of pulmonary microvascular endothelial cells with antihistamines prevented adhesion junction disruption; predictably, the combination of antiviral drug remdesivir with the antihistamine loratadine, a histamine receptor 1 (HR1) antagonist, dampened viral replication and inflammation, thereby greatly reducing lung injury. | remdesivir | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |