Title : Vitamin D Reduces Thyroid Cancer Cells Migration Independently From the Modulation of CCL2 and CXCL8 Chemokines Secretion.

Pub. Date : 2022

PMID : 35498406






5 Functional Relationships(s)
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1 Vitamin D Reduces Thyroid Cancer Cells Migration Independently From the Modulation of CCL2 and CXCL8 Chemokines Secretion. Vitamin D C-C motif chemokine ligand 2 Homo sapiens
2 The aim of the present study was to investigate if vitamin D could modulate both thyroid cancer cell migration and their ability to secrete CCL2 and CXCL8. Vitamin D C-C motif chemokine ligand 2 Homo sapiens
3 Vitamin D differently modulated the secretion of CCL2 and CXCL8, by significantly inhibiting the secretion of CCL2 in both thyroid cancer cell lines and inhibiting the secretion of CXCL8 only in TPC-1 (ANOVAs p < 0.05). Vitamin D C-C motif chemokine ligand 2 Homo sapiens
4 Vitamin D differently modulated the secretion of CCL2 and CXCL8, by significantly inhibiting the secretion of CCL2 in both thyroid cancer cell lines and inhibiting the secretion of CXCL8 only in TPC-1 (ANOVAs p < 0.05). Vitamin D C-C motif chemokine ligand 2 Homo sapiens
5 Future studies specifically designed at clarifying the pathways involved in the different inhibitory effects of vitamin D on CCL2 and CXCL8 in thyroid cancer cells appear worthwhile. Vitamin D C-C motif chemokine ligand 2 Homo sapiens