Title : RS 2247911 polymorphism of GPRC6A gene and serum undercarboxylated-osteocalcin are associated with testis function.

Pub. Date : 2022 Apr 28

PMID : 35482214






1 Functional Relationships(s)
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1 PURPOSE: Undercarboxylated-Osteocalcin (ucOCN), acting on its putative receptor GPRC6A, was shown to stimulate testosterone (T) production by Leydig cells in rodents, in parallel with the hypothalamus-pituitary-gonadal axis (HPG) mediated by luteinizing hormone (LH). Testosterone G protein-coupled receptor class C group 6 member A Homo sapiens