Pub. Date : 2022 Apr 27
PMID : 35477414
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A molecular dynamics perspective into estrogen receptor inhibition by selective flavonoids as alternative therapeutic options. | Flavonoids | estrogen receptor 1 | Homo sapiens |
| 2 | This study aimed to identity flavonoid ERalpha inhibitors and provide insights into the mechanism of inhibition using computational techniques. | Flavonoids | estrogen receptor 1 | Homo sapiens |
| 3 | The Molecular Mechanics/Generalized Born Surface Area calculations revealed that quercetrin, hesperidin, epigallocatechin 3-gallate and kaempferol 7-O-glucoside out of 14 flavonoids had higher binding affinity for ERalpha than OHT. | Flavonoids | estrogen receptor 1 | Homo sapiens |
| 4 | The results of this study provide imperative information that supports the use of flavonoids in the inhibition of ERalpha to prevent or ameliorate the consequential adverse effects associated with zearalenone exposure.Communicated by Ramaswamy H. Sarma. | Flavonoids | estrogen receptor 1 | Homo sapiens |