Pub. Date : 2022 May 12
PMID : 35477296
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structure and Orientation of the SARS-Coronavirus-2 Spike Protein at Air-Water Interfaces. | Water | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 2 | We here report on the secondary structure and orientation of the S1 segment of the spike protein, which is often used as a model protein for in vitro studies of SARS-CoV-2, at the air-water interface using surface-sensitive vibrational sum-frequency generation (SFG) spectroscopy. | Water | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 3 | The SFG experiments show that the S1 segment of the spike protein remains folded at the air-water interface and predominantly binds in its monomeric state, while the combination of small-angle X-ray scattering and two-dimensional infrared spectroscopy measurements indicate that it forms hexamers with the same secondary structure in aqueous solution. | Water | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |