Title : ARHGAP1 Transported with Influenza Viral Genome Ensures Integrity of Viral Particle Surface through Efficient Budozone Formation.

Pub. Date : 2022 Apr 27

PMID : 35475647






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 ARHGAP1 Transported with Influenza Viral Genome Ensures Integrity of Viral Particle Surface through Efficient Budozone Formation. budozone Rho GTPase activating protein 1 Homo sapiens
2 ARHGAP1 stabilized actin filaments in infected cells for the lateral clustering of hemagglutinin (HA) molecules, a viral surface membrane protein, to the budozone. budozone Rho GTPase activating protein 1 Homo sapiens
3 Collectively, these results demonstrate that Rab11a-mediated endocytic transport of ARHGAP1 with vRNPs stimulates budozone formation to ensure the integrity of virion surface required for viral survival. budozone Rho GTPase activating protein 1 Homo sapiens
4 Here, we found that ARHGAP1, a negative regulator of the Rho family protein, is transported with the viral genome and stabilizes actin filaments to promote budozone formation. budozone Rho GTPase activating protein 1 Homo sapiens