Pub. Date : 2022 Apr 27
PMID : 35475647
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | ARHGAP1 Transported with Influenza Viral Genome Ensures Integrity of Viral Particle Surface through Efficient Budozone Formation. | budozone | Rho GTPase activating protein 1 | Homo sapiens |
2 | ARHGAP1 stabilized actin filaments in infected cells for the lateral clustering of hemagglutinin (HA) molecules, a viral surface membrane protein, to the budozone. | budozone | Rho GTPase activating protein 1 | Homo sapiens |
3 | Collectively, these results demonstrate that Rab11a-mediated endocytic transport of ARHGAP1 with vRNPs stimulates budozone formation to ensure the integrity of virion surface required for viral survival. | budozone | Rho GTPase activating protein 1 | Homo sapiens |
4 | Here, we found that ARHGAP1, a negative regulator of the Rho family protein, is transported with the viral genome and stabilizes actin filaments to promote budozone formation. | budozone | Rho GTPase activating protein 1 | Homo sapiens |