Title : Targeting impaired autophagy as a therapeutic strategy for Koolen-de Vries syndrome.

Pub. Date : 2022 Apr 29

PMID : 35468045






1 Functional Relationships(s)
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1 Furthermore, we discovered an FDA-approved drug, 13-cis retinoic acid, is capable of alleviating these mitophagic defects and neurobehavioral abnormalities in Kansl1 heterozygous mice by promoting autophagosome-lysosome fusion via directly binding to STX17 and SNAP29. Isotretinoin KAT8 regulatory NSL complex subunit 1 Mus musculus