Pub. Date : 2022 Apr
PMID : 35464168
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UVA exposure increased the gene expression of IL-1alpha, the mRNA levels of MMP-1, and hence, the levels of MMP-1 protein in HaCaT cells, whereas cells treated with lotus polyphenol (LP) normalized these values to the control. | leucylproline | matrix metallopeptidase 1 | Homo sapiens |
| 2 | UVA exposure increased the gene expression of IL-1alpha, the mRNA levels of MMP-1, and hence, the levels of MMP-1 protein in HaCaT cells, whereas cells treated with lotus polyphenol (LP) normalized these values to the control. | leucylproline | matrix metallopeptidase 1 | Homo sapiens |
| 3 | In the presence of LP at concentrations of 1 and 10 mug/mL, both the secretion of IL-1alpha and protein levels of MMP-1 in human keratinocyte cells significantly reduced. | leucylproline | matrix metallopeptidase 1 | Homo sapiens |
| 4 | Our results with three different skin cells accordingly showed that LP may help maintain skin health through decreased levels of MMP-1 activity via its anti-inflammatory properties. | leucylproline | matrix metallopeptidase 1 | Homo sapiens |