Pub. Date : 2022 Jun
PMID : 35462331
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Midostaurin, identified as an ABCB1 inhibitor, increased anthracycline accumulation in peripheral blood mononuclear cells (PBMC) of CD34+ AML patients and those not achieving CR. | midostaurin | CD34 molecule | Homo sapiens |
| 2 | Overall, we highlight the therapeutic value of midostaurin as more than just a FLT3 inhibitor, suggesting its maximal therapeutic outcomes might be very sensitive to proper timing and well-optimized dosage schemes based upon patient"s characteristics, such as CD34 positivity and ABCB1 activity. | midostaurin | CD34 molecule | Homo sapiens |