Title : Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma.

Pub. Date : 2022 May

PMID : 35459782






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tipifarnib reduced HRAS processing, and plasma membrane localization leading to decreased GTP-bound HRAS and decreased signaling through RAS effector pathways. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens