Title : A Perspective for Ménière's Disease: In Silico Investigations of Dexamethasone as a Direct Modulator of AQP2.

Pub. Date : 2022 Mar 28

PMID : 35454100






2 Functional Relationships(s)
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1 We addressed this question through molecular dynamics simulations approaches and managed to demonstrate a direct interaction between AQP2 and dexamethasone and its significant impact on the channel water permeability. Water aquaporin 2 Homo sapiens
2 Through compartmentalization of sodium and potassium ions, a significant effect of Na+ upon AQP2 water permeability was highlighted as well. Water aquaporin 2 Homo sapiens