Title : Antitumor Efficacy of EGFR-Targeted Recombinant Immunotoxin in Human Head and Neck Squamous Cell Carcinoma.

Pub. Date : 2022 Mar 22

PMID : 35453686






1 Functional Relationships(s)
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1 hDT806 decreased EGFR protein levels and disrupted the EGFR signaling downstream effectors, including MAPK/ERK1/2 and AKT, while increased proapoptotic proteins, such as p53, caspase-9, caspase-3, and the cleaved PAPR. hdt806 mitogen-activated protein kinase 3 Mus musculus