Title : Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.

Pub. Date : 2022 Apr 21

PMID : 35449130






1 Functional Relationships(s)
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Protein Name
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1 While treatment with the Bcl-2 inhibitor Navitoclax results in the reduction of metastases in tumor bearing mice, treatment with the Mcl-1 inhibitor S63845 leads to complete elimination of senescent tumor cells and metastases. S63845 B cell leukemia/lymphoma 2 Mus musculus