Title : Effect of the Emulsion Solvent Evaporation Technique Cosolvent Choice on the Loading Efficiency and Release Profile of Anti-CD47 from PLGA Nanospheres.

Pub. Date : 2022 Apr 18

PMID : 35447106






1 Functional Relationships(s)
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1 Ethyl acetate was found to be the optimum cosolvent, improving the loading efficiency of anti-CD47 in poly(lactic-co-glycolic acid), PLGA, nanoparticles to 90% or higher, and the antibody was found to retain its activity after being released from nanoparticles. Polylactic Acid-Polyglycolic Acid Copolymer CD47 molecule Homo sapiens