Title : Group dynamics goes awry: PolyQ-expanded huntingtin gains unwanted partners.

Pub. Date : 2022 Apr 20

PMID : 35447076






3 Functional Relationships(s)
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1 Group dynamics goes awry: PolyQ-expanded huntingtin gains unwanted partners. polyglutamine huntingtin Homo sapiens
2 define high-confidence polyglutamine-dependent huntingtin interactors using AP-MS and complementary approaches and categorize them based on their interaction abundance and stability. polyglutamine huntingtin Homo sapiens
3 The study reveals that a toxic gain of polyQ-dependent Htt interacting partners is a robust feature of HD pathogenesis. polyglutamine huntingtin Homo sapiens