Title : Picolinamides and Iodoalkynes Enable Palladium-Catalyzed syn-Aminoalkynylation of Di- and Trisubstituted Alkenes to Give Pyrrolidines.

Pub. Date : 2022 Apr 21

PMID : 35445778






2 Functional Relationships(s)
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1 Picolinamides and Iodoalkynes Enable Palladium-Catalyzed syn-Aminoalkynylation of Di- and Trisubstituted Alkenes to Give Pyrrolidines. Pyrrolidines synemin Homo sapiens
2 The picolinamide auxiliary enables for the first time the syn -selective aminoalkynylation of mono-, di- and trisubstituted alkenes to afford the corresponding pyrrolidines in up to 97% yield and as single diastereomers. Pyrrolidines synemin Homo sapiens