Title : Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2.

Pub. Date : 2022

PMID : 35432786






1 Functional Relationships(s)
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1 Additionally, semi-stable docking of bisartans at the arginine-rich furin-cleavage site of the SARS-CoV-2 spike protein (residues 681-686) required for virus entry into host cells, suggest bisartans may inhibit furin action thereby retarding viral entry into host cells. Arginine surface glycoprotein Severe acute respiratory syndrome coronavirus 2