Title : Kaposi's sarcoma-associated herpes virus-derived microRNA K12-1 over-activates the PI3K/Akt pathway to facilitate cancer progression in HIV-related gastrointestinal Kaposi's sarcoma.

Pub. Date : 2022 Jun

PMID : 35413475






1 Functional Relationships(s)
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1 In addition, our rescuing experiments verified that miR-K12-1 promoted cell proliferation via activating the PI3K/Akt pathway, and inhibition of the PI3K/Akt pathway by LY294002 abrogated the tumor-promoting effects of miR-K12-1 in HIV-related gastrointestinal KS. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one AKT serine/threonine kinase 1 Homo sapiens