Title : Targets Exploration of Hydroxychloroquine for Pigmentation and Cell Protection Effect in Melanocytes: The Clue for Vitiligo Treatment.

Pub. Date : 2022

PMID : 35411132






2 Functional Relationships(s)
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1 Results: Molecular docking analysis revealed four putative key targets (ACHE, PNMT, MC1R, and VDR) of HCQ played important roles in vitiligo treatment. Hydroxychloroquine melanocortin 1 receptor Homo sapiens
2 The protective effects of HCQ are mediated by binding to putative targets ACHE, PNMT, MC1R, and VDR according to network pharmacology and docking verification. Hydroxychloroquine melanocortin 1 receptor Homo sapiens