Pub. Date : 2022 May 13
PMID : 35410483
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Adenosine supplementation activated AMPK and abolished SAHH deficiency-induced expression of H19 and Runx2 and osteoblastic differentiation of VSMCs. | Adenosine | H19 imprinted maternally expressed transcript | Homo sapiens |
2 | Finally, AMPK activation by adenosine inhibited H19 expression by inducing Sirt1-mediated histone H3 hypoacetylation and DNMT3b-mediated hypermethylation of the H19 promoter in SAHH deficiency VSMCs. | Adenosine | H19 imprinted maternally expressed transcript | Homo sapiens |
3 | Finally, AMPK activation by adenosine inhibited H19 expression by inducing Sirt1-mediated histone H3 hypoacetylation and DNMT3b-mediated hypermethylation of the H19 promoter in SAHH deficiency VSMCs. | Adenosine | H19 imprinted maternally expressed transcript | Homo sapiens |