Pub. Date : 2022 Apr 19
PMID : 35397208
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we reconstituted an in vitro pseudovirus-liposome fusion reaction and report that SARS-CoV-2 wild-type spike is a dynamic Ca2+ sensor, and D614G mutation enhances dynamic calcium sensitivity of spike protein for facilitating membrane fusion. | Calcium | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 2 | Here, we reconstituted an in vitro pseudovirus-liposome fusion reaction and report that SARS-CoV-2 wild-type spike is a dynamic Ca2+ sensor, and D614G mutation enhances dynamic calcium sensitivity of spike protein for facilitating membrane fusion. | Calcium | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 3 | This dynamic calcium sensitivity for fusion is found to be higher in Alpha and Beta variants and highest in Delta spike variant. | Calcium | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |