Title : The IRE1α Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes.

Pub. Date : 2022

PMID : 35392553






1 Functional Relationships(s)
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1 Here we report that the potent IRE1alpha inhibitor, KIRA6, blocks leukotriene biosynthesis in human phagocytes activated with lipopolysaccharide (LPS) plus N-formyl-methionyl-leucyl-phenylalanine (fMLP) or thapsigargin (Tg). Leukotrienes formyl peptide receptor 1 Homo sapiens