Title : Metformin Promotes Differentiation and Attenuates H2O2-Induced Oxidative Damage of Osteoblasts via the PI3K/AKT/Nrf2/HO-1 Pathway.

Pub. Date : 2022

PMID : 35387349






1 Functional Relationships(s)
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1 We added LY294002 to inhibit the PI3K/AKT pathway, and the results indicated that the osteogenic effect of metformin was also blocked. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one AKT serine/threonine kinase 1 Homo sapiens