Title : Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway.

Pub. Date : 2022

PMID : 35370723






3 Functional Relationships(s)
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1 Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway. irisin nuclear factor, erythroid derived 2, like 2 Mus musculus
2 The aim of this study was to verify the occurrence of ferroptosis in the SA-AKI pathogenesis and demonstrate that post-treatment with irisin could restrain ferroptosis and alleviate SA-AKI via activating the SIRT1/Nrf2 signaling pathway. irisin nuclear factor, erythroid derived 2, like 2 Mus musculus
3 Furthermore, our result also revealed that irisin could activate SIRT1/Nrf2 signaling pathways both in vivo and vitro. irisin nuclear factor, erythroid derived 2, like 2 Mus musculus