Pub. Date : 2022
PMID : 35370723
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway. | irisin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
2 | The aim of this study was to verify the occurrence of ferroptosis in the SA-AKI pathogenesis and demonstrate that post-treatment with irisin could restrain ferroptosis and alleviate SA-AKI via activating the SIRT1/Nrf2 signaling pathway. | irisin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
3 | Furthermore, our result also revealed that irisin could activate SIRT1/Nrf2 signaling pathways both in vivo and vitro. | irisin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |