Pub. Date : 2022
PMID : 35370657
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Liquorice Extract and 18beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation. | 18alpha-glycyrrhetinic acid | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | Further mechanism study showed that GA inhibited activities of CYPs, especially CYP3A1, the major CYP isoform responsible for the metabolic activation of RTS in rats. | 18alpha-glycyrrhetinic acid | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |