Title : Tetracyclines Enhance Anti-tumor T-Cell Responses Induced by a Bispecific T-Cell Engager.

Pub. Date : 2022

PMID : 35370267






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 By using bispecific T-cell engager technology to assess the cytotoxicity of peripheral T cells against tumor cells, we showed that tetracyclines (minocycline, tetracycline, doxycycline, meclocycline, chlortetracycline, and demeclocycline) enhanced T-cell cytotoxicity through granzyme B expression and CD4+ and CD8+ T-cell proliferation. Tetracyclines CD8a molecule Homo sapiens