Title : Pectin coated nanostructured lipid carriers for targeted piperine delivery to hepatocellular carcinoma.

Pub. Date : 2022 May 10

PMID : 35367582






3 Functional Relationships(s)
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1 In this study, positively charged PIP-loaded nanostructured lipid carriers (PIP-NLCs) were prepared via melt-emulsification and ultra-sonication method followed by pectin coating to get novel pectin-coated NLCs (PIP-P-NLCs) targeting hepatocellular carcinoma. piperine inositol polyphosphate-5-phosphatase J Homo sapiens
2 Furthermore, PIP-P-NLCs improved in vivo anticancer effect of PIP as proved by histological examination of liver tissues, suppression of liver enzymes and oxidative stress environment in the liver, and alteration of cell cycle regulators. piperine inositol polyphosphate-5-phosphatase J Homo sapiens
3 To conclude, PIP-P-NLCs can act as a promising approach for targeted delivery of PIP to hepatocellular carcinoma. piperine inositol polyphosphate-5-phosphatase J Homo sapiens