Title : Altered propionate metabolism contributes to tumour progression and aggressiveness.

Pub. Date : 2022 Apr

PMID : 35361954






1 Functional Relationships(s)
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1 The loss of MCEE results in reduced propionate-driven anaplerotic flux and intracellular and intratumoral accumulation of methylmalonic acid, a by-product of propionate metabolism that promotes cancer cell invasiveness. Methylmalonic Acid methylmalonyl-CoA epimerase Homo sapiens